ea0092ps1-09-08 | Thyroid Cancer | ETA2023
Ignjatović Jocić Valentina
, Janković Miljuš Jelena
, Roncevic Jelena
, Tatić Svetilsav
, Išić Denčić Tijana
, Đorić Ilona
, Selemetjev Sonja
Objective: Focal adhesion kinase (FAK) is non-receptor tyrosine kinase that has been shown to affect cell motility, adhesion, invasion, cell survival, proliferation and de-differentiation. Its increased expression has been reported for various types of malignancies and is associated with cancer progression. However, there are less information regarding its posttranslational form, phosphorylated at Tyrosine 397 (pY397-FAK), which represents a key event for complete protein acti...